Chemical profile of the hydroalcoholic extract of Cecropia spp and its antimicrobial activity

Authors

DOI:

https://doi.org/10.19136/jobs.a11n30.6411

Keywords:

Cecropia peltata, Cecropia obtusifolia, HPLC-DAD, antimicrobial activity

Abstract

Antimicrobial resistance represents a global health problem, because microorganisms have developed mechanisms that allow inhibiting the activity of antimicrobial drugs as a result of their misuse, increasing the risk of complications in infectious diseases. In this sense, the objective of this work was to determine the chemical profile of Cecropia spp leaves by High Performance Liquid Chromatography coupled a Diode Array Detector (HPLC-DAD), where the presence of chlorogenic acid, isoorientin, orientin, a vitexin analogue and catechin were observed. In addition, the antimicrobial activity was evaluated by broth microdilution, where the C. peltata extract was active against 5 gram-positive and 2 gram-negative strains at concentrations <50 mg/mL and in the case of C. obtusifolia it was active against 4 gram-positive, 3 gram-negative and the fungus at concentrations <50 mg/mL, which may be related to the presence of chemical markers in Cecropia spp.

Author Biography

  • Eric Jaziel Medrano-Sánchez, División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km. 0.5, Cunduacán 86690, Tabasco, México.

    Doctor en Ciencias con Orientación en Química Orgánica

References

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Published

2025-04-30

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Artículo científico

How to Cite

Medrano-Sánchez, E. J., Bravata-Silván, S. J., Lobato-García, C. E. ., Gómez-Rivera, A. ., López-Rodríguez, R., Gallegos-García, A. J. ., González-Cortazar, M., Pérez-García, M. D., & Zamilpa, A. . (2025). Chemical profile of the hydroalcoholic extract of Cecropia spp and its antimicrobial activity. JOURNAL OF BASIC SCIENCES, 11(30), 84-92. https://doi.org/10.19136/jobs.a11n30.6411