Determination of phthalates in PET-packaged beverages using an MSFIA method coupled with HPLC-DAD

Authors

  • Willmann A Jiménez Morales National Autonomous University of Mexico image/svg+xml
  • Laura Hinojosa Reyes Autonomous University of Nuevo León image/svg+xml
  • Jorge L Guzmán Mar Autonomous University of Nuevo León image/svg+xml
  • María P Cañizares Macías National Autonomous University of Mexico image/svg+xml
  • Salvador Aristeo Segura Universidad Autónoma “Benito Juárez” de Oaxaca

DOI:

https://doi.org/10.19136/jobs.a10n29.6367

Keywords:

Phthalates, preconcentrate, MSFIA, HPLC-DAD, juices

Abstract

In this work, an online preconcentration method was designed, optimized, and validated using a C18-type membrane with a Multisyrup Flow Injection Analysis (MSFIA) system coupled to HPLC-DAD equipment for the determination of contaminants derived from phthalic acid esters (DMP, DEP, and DBP) in juices stored in PET bottles. The physicochemical and hydrodynamic parameters of the method were optimized using a central composite experiment design. The method showed good precision (˂3%), a LOD of less than 0.5 μg kg–1, and a preconcentration factor of 33 times. After applying the method to 4 samples of juices, concentrations of 172.89 and 100.43 μg kg–1 of DMP and DBP were identified and quantified, respectively. Finally, recovery values that ranged between 44.12% and 141.07% were obtained for the three phthalates.

References

E. Fasano, F. Bono-Blay, T. Cirillo, P. Montuori, y S. Lacorte, “Migration of phthalates, alkylphenols, bisphenol A and di(2-ethylhexyl)adipate from food packaging”, Food Control, vol. 27, núm. 1, pp. 132–138, sep. 2012, doi: 10.1016/j.foodcont.2012.03.005. DOI: https://doi.org/10.1016/j.foodcont.2012.03.005

M. Wagner y J. Oehlmann, “Endocrine disruptors in bottled mineral water: Total estrogenic burden and migration from plastic bottles”, Environmental Science and Pollution Research, vol. 16, núm. 3, pp. 278–286, may 2009, doi: 10.1007/s11356-009-0107-7. DOI: https://doi.org/10.1007/s11356-009-0107-7

W. J. G. M. Peijnenburg y J. Struijs, “Occurrence of phthalate esters in the environment of the Netherlands”, Ecotoxicol Environ Saf, vol. 63, núm. 2, pp. 204–215, feb. 2006, doi: 10.1016/j.ecoenv.2005.07.023. DOI: https://doi.org/10.1016/j.ecoenv.2005.07.023

M. J. Silva et al., “Analysis of human urine for fifteen phthalate metabolites using automated solid-phase extraction”, J Chromatogr B Analyt Technol Biomed Life Sci, vol. 805, núm. 1, pp. 161–167, jun. 2004, doi: 10.1016/j.jchromb.2004.02.038. DOI: https://doi.org/10.1016/j.jchromb.2004.02.038

K. Khosravi y G. W. Price, “Determination of phthalates in soils and biosolids using accelerated solvent extraction coupled with SPE cleanup and GC-MS quantification”, Microchemical Journal, vol. 121, pp. 205–212, jul. 2015, doi: 10.1016/j.microc.2015.03.013. DOI: https://doi.org/10.1016/j.microc.2015.03.013

Y. Guo, Q. Wu, y K. Kannan, “Phthalate metabolites in urine from China, and implications for human exposures”, Environ Int, vol. 37, núm. 5, pp. 893–898, 2011, doi: 10.1016/j.envint.2011.03.005. DOI: https://doi.org/10.1016/j.envint.2011.03.005

H. Fromme et al., “Intake of phthalates and di(2-ethylhexyl)adipate: Results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data”, Environ Int, vol. 33, núm. 8, pp. 1012–1020, 2007, doi: 10.1016/j.envint.2007.05.006. DOI: https://doi.org/10.1016/j.envint.2007.05.006

Y. Gao, T. An, Y. Ji, G. Li, y C. Zhao, “Eco-toxicity and human estrogenic exposure risks from .OH-initiated photochemical transformation of four phthalates in water: A computational study”, Environmental Pollution, vol. 206, pp. 510–517, nov. 2015, doi: 10.1016/j.envpol.2015.08.006. DOI: https://doi.org/10.1016/j.envpol.2015.08.006

M. Rahman y C. S. Brazel, “The plasticizer market: An assessment of traditional plasticizers and research trends to meet new challenges”, Progress in Polymer Science (Oxford), vol. 29, núm. 12. pp. 1223–1248, diciembre de 2004. doi: 10.1016/j.progpolymsci.2004.10.001. DOI: https://doi.org/10.1016/j.progpolymsci.2004.10.001

P. Otero, S. K. Saha, S. Moane, J. Barron, G. Clancy, y P. Murray, “Improved method for rapid detection of phthalates in bottled water by gas chromatography-mass spectrometry”, J Chromatogr B Analyt Technol Biomed Life Sci, vol. 997, pp. 229–235, ago. 2015, doi: 10.1016/j.jchromb.2015.05.036. DOI: https://doi.org/10.1016/j.jchromb.2015.05.036

D. Salazar-Beltrán, L. Hinojosa-Reyes, E. Ruiz-Ruiz, A. Hernández-Ramírez, y J. Luis Guzmán-Mar, “Determination of phthalates in bottled water by automated on-line solid phase extraction coupled to liquid chromatography with uv detection”, Talanta, vol. 168, pp. 291–297, jun. 2017, doi: 10.1016/j.talanta.2017.03.060. DOI: https://doi.org/10.1016/j.talanta.2017.03.060

Y. T. Wu et al., “Selective and simultaneous determination of trace bisphenol A and tebuconazole in vegetable and juice samples by membrane-based molecularly imprinted solid-phase extraction and HPLC”, Food Chem, vol. 164, pp. 527–535, dic. 2014, doi: 10.1016/j.foodchem.2014.05.071. DOI: https://doi.org/10.1016/j.foodchem.2014.05.071

A. S. Alnaimat, M. C. Barciela-Alonso, y P. Bermejo-Barrera, “Determination of bisphenol A in tea samples by solid phase extraction and liquid chromatography coupled to mass spectrometry”, Microchemical Journal, vol. 147, pp. 598–604, jun. 2019, doi: 10.1016/j.microc.2019.03.026. DOI: https://doi.org/10.1016/j.microc.2019.03.026

J. Li, Y. Cai, Y. Shi, S. Mou, y G. Jiang, “Analysis of phthalates via HPLC-UV in environmental water samples after concentration by solid-phase extraction using ionic liquid mixed hemimicelles”, Talanta, vol. 74, núm. 4, pp. 498–504, ene. 2008, doi: 10.1016/j.talanta.2007.06.008. DOI: https://doi.org/10.1016/j.talanta.2007.06.008

L. Chang, P. Bi, X. Li, y Y. Wei, “Study of solvent sublation for concentration of trace phthalate esters in plastic beverage packaging and analysis by gas chromatography-mass spectrometry”, Food Chem, vol. 177, pp. 127–133, jun. 2015, doi: 10.1016/j.foodchem.2015.01.013. DOI: https://doi.org/10.1016/j.foodchem.2015.01.013

Z. Guo, D. Wei, M. Wang, y S. Wang, “Determination of Six Phthalic Acid Esters inOrange Juice Packaged by PVC Bottle Using SPEand HPLC–UV: Application to the Migration Study”, J Chromatogr Sci, vol. 48, núm. 9, pp. 760–765, oct. 2010, doi: 10.1093/chromsci/48.9.760. DOI: https://doi.org/10.1093/chromsci/48.9.760

J. Li, Y. Cai, Y. Shi, S. Mou, y G. Jiang, “Analysis of phthalates via HPLC-UV in environmental water samples after concentration by solid-phase extraction using ionic liquid mixed hemimicelles”, Talanta, vol. 74, núm. 4, pp. 498–504, ene. 2008, doi: 10.1016/j.talanta.2007.06.008. DOI: https://doi.org/10.1016/j.talanta.2007.06.008

X. Gao et al., “Determination of phthalates released from paper packaging materials by solid-phase extraction-high-performance liquid chromatography”, J Chromatogr Sci, vol. 52, núm. 5, pp. 383–389, may 2014, doi: 10.1093/chromsci/bmt046. DOI: https://doi.org/10.1093/chromsci/bmt046

S. Clavijo, J. Avivar, R. Suárez, y V. Cerdà, “Analytical strategies for coupling separation and flow-injection techniques”, TrAC - Trends in Analytical Chemistry, vol. 67. Elsevier B.V., pp. 26–33, el 1 de abril de 2015. doi: 10.1016/j.trac.2014.11.019. DOI: https://doi.org/10.1016/j.trac.2014.11.019

J. N Miller y J. C Miller, Statistics and Chemometrics for Analytical Chemistry, Sixth edit. England: Pearson Education Limited, 2010. [En línea]. Disponible en: www.pearsoned.co.uk

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Published

2024-12-16

Issue

Vol. 10 No. 29 (2024): Journal of Basic Sciences

Section

Artículo científico

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How to Cite

Jiménez Morales, W. A., Hinojosa Reyes, L., Guzmán Mar , J. L., Cañizares Macías, M. P., & Aristeo Segura, S. (2024). Determination of phthalates in PET-packaged beverages using an MSFIA method coupled with HPLC-DAD. JOURNAL OF BASIC SCIENCES, 10(29), 1-16. https://doi.org/10.19136/jobs.a10n29.6367